The barbiturates are non-selective depressants used in the central nervative system primarily as sedative hypnotics and subhypnotic anticonvulsants. The Federal Controlled Substances Act regulates barbiturates and sodium salts. The sterile parenteral solutions are available in sodium salts of amobarbital, pentobarbital, phenobarbital and secobarbital. You can buy 01Nembutal Pentobarbital Sodium 50mg/Ml online for sale.
Barbiturates are replaced by pyrimidine derivatives with Barbituric acid, which has no central nervous system (CNS) function, as the basic structure specific to these drugs. CNS activity is accomplished on the pyrimidine ring by the substitution of alkyl, alkenyl or aryl groups. NEMBUTAL Sodium Solution (pentobarbital sodium injection) is a sterile injection drug. The pH is regulated to around 9,5 with sodium and hydrochloric acid.
The sodium solution should be kept to a minimum in convulsive states in order to prevent the compounding of stress that may accompany convulsions. The injection must be performed gradually with due consideration of the time required to cross the blood-brain barrier for the drug.
Dosages should be decreased or diminished in the elderly because these patients are potentially more prone to barbiturates. Dose reduction may occur in patients with liver disease.
Barbiturate dosages should be individualised and their basic properties should be thoroughly known and their prescribed dosage rate approved. Patient age, weight and condition are considered. Only if oral administration is not feasible or desirable can parental routes be used.
IM injection of barbiturate salts into a large muscle should be rendered deeply and no more than 5 mL at one location should be exceeded due to the potential inflammation of the tissue. The patient's vital signs should be tracked after IM injection of the hypnotic dose. NEMBUTAL(pentobarbital) sodium solution is typically adult injected at a dosage of 150 to 200 mg per IM single, and the recommended pediatric dosage varies between 2 and 6 mg / kg per IM single injection, not exceeding 100 mg.
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